Name:CSTMiner_in_JST
Description:CSTMiner is a tool for a comprehensive comparison genomes performed with a new high throughput grid-based system which allows the rapid detection of conserved sequences and accurate assessment of their coding potential. By detecting clusters of coding conserved sequences the system is also suitable to accurately identify potential gene loci.
The accurate detection of genes and the identification of functional regions is still an open issue in the annotation of genomic sequences. This problem affects new genomes but also those of very well studied organisms such as human and mouse where, despite the great efforts, the inventory of genes and regulatory regions is far from complete.
With this tool a collection of human-mouse conserved sequence tags was created. Several potential gene loci supported by EST sequences not corresponding to as yet annotated genes were detected.
The tool does not require the availability of any annotated sequence thus is suitable for the analysis of new or poorly annotated genomes.
Abstract:CSTMiner is a tool for a comprehensive comparison genomes performed with a new high throughput grid-based system which allows the rapid detection of conserved sequences and accurate assessment of their coding potential. By detecting clusters of coding conserved sequences the system is also suitable to accurately identify potential gene loci.
The accurate detection of genes and the identification of functional regions is still an open issue in the annotation of genomic sequences. This problem affects new genomes but also those of very well studied organisms such as human and mouse where, despite the great efforts, the inventory of genes and regulatory regions is far from complete.
With this tool a collection of human-mouse conserved sequence tags was created. Several potential gene loci supported by EST sequences not corresponding to as yet annotated genes were detected.
The tool does not require the availability of any annotated sequence thus is suitable for the analysis of new or poorly annotated genomes.

Created:2010-05-01
Last updated:2013-09-04