Description:Monte Carlo study of polymer translocation
Abstract:The transport of biopolymers through large membrane channels is a ubiquitous process in biology. It is central to processes such as gene transfer by transduction and RNA transport through nuclear pore complexes. The transport of polymers through nanoscopic channels is also of interest to physicists and chemists studying the effects of steric, hydrodynamic, and electrostatic interactions between polymers and confining walls.
Our work aim to characterize polymer translocation through a nanopore under the influence of an external electric field.
Particularly, we investigate the relationship between the translocation time and physics quantities, such as the channel length, the applied electric field, the temperature, the chain stiffness and the interactions between channel and polymer.
For this purpose, we utilized a Monte Carlo approach, based on the Bond Fluctuation model, accounting for the contribute of a potential energy depending on the angles between adjacent bonds (chain stiffness) and of a discrete \ quasi-Lennard-Jones\ potential which models the interactions between non-adjacent monomers (quality of the solvent).
<BR><BR><B>Software requirements</B>: Fortran compiler