Description:Parallel Blood Flow Simulation
Abstract:A computational model of realistic blood flow in a section of artery could improve diagnosis and treatment of health problems such as aneurysms and wounds to artery vessel walls. Systems of equations describing fluid and wall behavior are numerically simulated in Center for Scientific Research of Serbian Academy of Science and Art and University of Kragujevac with parallel computational software environment for solving equations using finite element analysis. These systems include Navier-Stokes and incompressible fluid equations coupled through boundary conditions to the deformable wall motion using fluid-structure interactions.
Modeling of thrombosis in blood vessels using Dissipativa Particle Dynamics has been developed. Blood is modeled as a two-phase, nonhomogeneous fluid, consisting of a liquid plasma phase and blood cells as elastically deformable solids. The plasma, rich in many other blood components such as lipids, enzymes, and platelets, cannot be studied at the microscale as a continuous medium but rather as an electrolytic suspension with many microstructural components. The multiscale modeling includes coupling between events on nanoscale, such as kinetics of binding, motion and deformation of red blood cells and platelet aggregation and adhesion as meso-scale events, and blood flow in large blood vessels as macro-scale events in a continnuum. This new computational technique requires a massive parallel computing for simulation of this complex biological problem.